Simulated, Natural and Lab Created Gemstones What's the difference? Well, it's pretty simple. Gemstones can be natural, lab created or simulated. Natural and lab created gemstones have the same physical, optical and chemical properties. Simulated refers to a created stone that looks similar in appearance to a genuine gemstone, but has different physical, optical and chemical properties. Lab created stones are an affordable way to own a genuine gemstone. The only difference between natural and lab created is that the lab created stones were not mined from the earth. Tip: When buying someone jewelry as a gift find out what their birthstone is. I hope this information has been helpful. Remember to be safe when shopping from anyone you don’t know. And have fun!